Award
National Institute of Allergy and Infectious Diseases 5R01AI186995-02
Molecular characterization and modeling efficient antibody effector function
Recipient
Dartmouth College, Hanover, NH, United States
Award Amount
$442,024.00
Ceiling
$442,024.00
Awarded
December 05, 2025
Identifier
5R01AI186995-02
A multi-year funded project by NIAID at Dartmouth College to study and model antibody effector functions to improve immune therapeutics and antibody design.
Description
This project aims to elucidate cellular mechanisms that can drive advancements in immune therapeutics by establishing quantitative relationships between antigen, antibody, and effector biology to generate predictive rules for antibody design. It involves studying antibody effector functions, including ADCC and phagocytosis, to guide antibody immunotherapies.