Award
NIH Reporter #1R21AI199907-01
Anopheles salivary antigen to measure the effectiveness of permethrin-treated baby wraps for the prevention of malaria: secondary analysis of a randomized controlled trial.
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL, CHAPEL HILL, NC, UNITED STATES
Award Amount
$433,977.00
Ceiling
$433,977.00
Awarded
August 10, 2026
Identifier
1R21AI199907-01
The study tests human antibodies against Anopheles mosquito salivary antigens to confirm the protective effect of permethrin-treated baby wraps against malaria in children, based on a prior randomized trial in Uganda.
Description
This project involves analyzing blood samples for antibody responses to mosquito salivary antigens as a surrogate for mosquito exposure, aiming to confirm the mechanism of malaria prevention via permethrin-treated wraps and to validate a novel biomarker for malaria-related studies.