Award
NIH Reporter #5I01CX002707-02
BCCMA: VA Colorectal Cancer Clinical & Computational Collaborative (VA-5C): NIR-labeled antibodies to target and label colon polyps and cancer for improved diagnosis and surgery
Recipient
Not specified
Awarded
July 27, 2026
Identifier
5I01CX002707-02
Award for developing near-infrared labeled antibodies to improve diagnosis and surgery of colorectal cancer, including plans for clinical trials.
Description
The project focuses on developing tumor-specific near-infrared fluorescence labeling of premalignant polyps and colorectal cancer using genetically engineered mouse models and patient-derived orthotopic xenograft models. The goal is to improve diagnosis and surgical outcomes for colorectal cancer, with plans for clinical trials of fluorescent anti-mucin antibody-based fluorescence-guided surgery.