Award
NIH Reporter #11575645
Effectiveness of an Early Intensive Preventive Dental Program by Oncology Providers to Reduce Dental Disease and Improve Compliance in Head and Neck Cancer Patients: OraRad IPDP
Recipient
Wake Forest University Health Sciences
Award Amount
$1,657,346.00
Ceiling
$1,657,346.00
Awarded
September 17, 2026
Identifier
11575645
This award funds a clinical trial led by Wake Forest University Health Sciences to test an early intensive preventive dental program for head and neck cancer patients. The program aims to reduce dental disease and improve patient compliance by integrating fluoride varnish application and dental screenings into oncology follow-ups.
Description
A randomized clinical trial testing an intervention of topical fluoride varnish application and dental screening during oncology follow-up visits for head and neck cancer patients to reduce dental disease and improve compliance with preventive dental care. The intervention includes application of fluoride varnish by medical team members and dental referral for signs of dental disease. The primary outcome is dental caries progression (DMFS), with secondary outcomes including tooth loss, oral health-related quality of life, and compliance with dental care.