Award
National Heart, Lung, and Blood Institute 5R01HL155426-04
Hematopoiesis in germline RUNX1 mutation carriers: impact of inflammation and the bone marrow niche
Recipient
Oregon Health & Science University
Award Amount
$504,283.00
Ceiling
$504,283.00
Awarded
June 05, 2024
Identifier
5R01HL155426-04
NIH grant awarded to Oregon Health & Science University to study hematopoiesis in germline RUNX1 mutation carriers, focusing on inflammation and bone marrow niche effects to develop leukemia prevention therapies.
Description
This project focuses on understanding the impact of inflammation and the bone marrow microenvironment on hematopoiesis in germline RUNX1 mutation carriers, with the goal of developing therapeutic strategies to prevent leukemia.