Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5K08AR083015-04
The Role of the Gut Microbiome in Post-Sepsis Skeletal Muscle Atrophy
Recipient
University of Iowa, Iowa City, IA, United States
Award Amount
$166,428.00
Ceiling
$166,428.00
Awarded
April 17, 2026
Identifier
5K08AR083015-04
Research project funded by NIAMS to investigate the gut microbiome's role in muscle atrophy after sepsis, aiming to find new treatment targets.
Description
This project will study how the gut microbiome contributes to muscle atrophy during sepsis, aiming to identify new targets for treatment. It involves in vivo and in vitro models with metabolomics and metagenomics techniques to identify bacterial taxa and metabolites involved in muscle atrophy, with potential future applications in human treatments.