Award
National Heart, Lung, and Blood Institute 5R01HL172846-03
IL-1R1 in Endothelial-to-Mesenchymal Activation
Recipient
University of Nebraska Medical Center
Award Amount
$446,848.00
Ceiling
$446,848.00
Awarded
February 16, 2026
Identifier
5R01HL172846-03
This NIH-funded project studies how IRAK1 regulates endothelial cell changes leading to atherosclerosis, with potential to identify new treatments for heart disease.
Description
Research project investigating the role of IRAK1 in endothelial-to-mesenchymal transition (EndMT) induced by disturbed blood flow, aiming to understand mechanisms and therapeutic targets for atherosclerosis.