Award
National Institute of Allergy and Infectious Diseases 5R01AI173565-03
Protective antibody in streptococcal infection models
Recipient
New York Medical College
Award Amount
$591,266.00
Ceiling
$591,266.00
Awarded
December 09, 2025
Identifier
5R01AI173565-03
This NIH/NIAID funded research project focuses on developing a vaccine against Group A streptococci by identifying protective antibodies and testing vaccine candidates in mouse models to reduce morbidity and mortality from GAS infections.
Description
The project aims to identify effective antigens for vaccine development against Group A streptococci (GAS). It involves analyzing serum from children and adults to determine protective antibody responses, and testing these in mouse models for protection against various GAS diseases. The work will establish correlates of protection and develop platforms for future vaccine candidate evaluation.