Award
National Institute on Aging 5K23AG073528-05
The effects of cumulative concussion, repetitive head impacts, and comorbid cardiovascular risk factors on MRI metrics of pathological aging and neurobehavioral functioning across the lifespan
Recipient
Medical College of Wisconsin, Milwaukee, WI, United States
Award Amount
$132,171.00
Ceiling
$132,171.00
Awarded
July 29, 2025
Identifier
5K23AG073528-05
This award funds research to study how repeated concussions and cardiovascular risk factors affect brain aging and neurobehavioral function using MRI across different ages. The goal is to understand the long-term neurological impact of mild traumatic brain injuries and repetitive head impacts.
Description
Exposure to mild traumatic brain injury (mTBI) and repetitive head impacts (RHI) during sport participation has been associated with adverse long-term consequences such as cognitive decline. This project aims to determine the influence of mTBI/RHI on MRI metrics of pathological aging and neurobehavioral function across the lifespan, considering the independent influence of increasing age and cardiovascular risk factors. The research will provide insight into the process underlying cumulative head injury and neurological decline later in life.