Award
National Eye Institute (NEI), National Human Genome Research Institute (NHGRI) 5R01EY029130-08
Structural, mechanical, and cell biological properties of the ciliary zonule
Recipient
Washington University
Award Amount
$474,844.00
Ceiling
$474,844.00
Awarded
April 01, 2026
Identifier
5R01EY029130-08
NIH grant awarded to Washington University for research on the structural, mechanical, and cell biological properties of the ciliary zonule, focusing on eye diseases and related genetic models.
Description
This is a NIH grant opportunity for research on the properties of the ciliary zonule, including modeling of zonulopathies, measurement of intraocular pressure, and analysis of zonular proteins such as LOXL1. The project involves imaging, material testing, and genetic models in mice, with a focus on eye diseases such as Marfan Syndrome, Weill-Marchesani Syndrome, and ectopia lentis.