Award
NIH Reporter #5R01GM151072-04
Regulation and feedback in Fat/Dachsous signaling
Recipient
University of Wisconsin-Madison, Madison, WI, United States
Award Amount
$309,354.00
Ceiling
$309,354.00
Awarded
May 18, 2026
Identifier
5R01GM151072-04
This NIH grant funds research on the regulation and feedback mechanisms in the Fat/Dachsous signaling pathway in Drosophila melanogaster, with implications for understanding human neurological and multisystem disorders.
Description
The project investigates the regulation of cell signaling pathways involving Fat and Dachsous (Ds) protocadherins in Drosophila melanogaster, which are linked to human neurological and multisystem disorders. The research aims to elucidate the molecular mechanisms of pathway regulation, cell polarization, and their implications in development and pathology.