Award
NIH Reporter #5R01AR070736-08
Uncovering the role of Setbp1 in fibroblast-like synoviocytes during inflammatory arthritis
Recipient
Emory University, Atlanta, GA, United States
Award Amount
$415,871.00
Ceiling
$415,871.00
Awarded
July 30, 2026
Identifier
5R01AR070736-08
Research project funded by NIAMS to study the role of SETBP1 in fibroblast-like synoviocytes during inflammatory arthritis, aiming to identify therapeutic targets for rheumatoid arthritis.
Description
This project aims to investigate the role of the epigenetic hub protein SETBP1 in regulating the epigenomic signature of fibroblast-like synoviocytes (FLS) in rheumatoid arthritis. The research will focus on understanding how SETBP1 influences gene expression related to inflammation and joint degeneration, with the goal of identifying SETBP1 as a potential therapeutic target.