Award
National Institute of Allergy and Infectious Diseases 5R21AI187895-02
MSC exosomes as probes for ME/CSF immune cell dysfunction
Recipient
Nova Southeastern University, Fort Lauderdale-Davie, FL
Award Amount
$192,500.00
Ceiling
$192,500.00
Awarded
December 01, 2025
Identifier
5R21AI187895-02
Research grant to study mesenchymal stromal cell-derived exosomes' effects on immune cells and mitochondrial function in ME/CFS patients to find therapeutic targets.
Description
This project proposes to study the effects of mesenchymal stromal cell-derived exosomes on immune cell subsets and mitochondrial function in PBMCs from ME/CFS patients to elucidate underlying pathology and identify novel therapeutic targets using exosomes as immunomodulators.