Award
National Institute of General Medical Sciences 5P20GM125528-07
The role of B cell estrogen signaling in menopause-associated metabolic dysfunction
Recipient
UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, Oklahoma City, OK, United States
Award Amount
$257,400.00
Ceiling
$257,400.00
Awarded
June 30, 2026
Identifier
5P20GM125528-07
A research project funded by the National Institute of General Medical Sciences to study the impact of B cell estrogen signaling on menopause-related metabolic dysfunction, focusing on weight gain and insulin resistance mechanisms.
Description
This research project investigates how estrogen signaling in B cells affects metabolic dysfunction associated with menopause, including weight gain and insulin resistance. The study aims to understand the role of B cell estrogen receptor alpha in adipose tissue inflammation and metabolic changes during menopause, potentially uncovering novel immune regulators of adipose tissue expansion and age-related diseases.