Award
National Institute of Diabetes and Digestive and Kidney Diseases 5K08DK134761-03
Evidence For Endothelial Involvement in Idiopathic Nephrotic Syndrome: A Role for CD93
Recipient
RESEARCH INST NATIONWIDE CHILDREN'S HOSP
Award Amount
$153,651.00
Ceiling
$153,651.00
Awarded
March 27, 2026
Identifier
5K08DK134761-03
This NIH grant supports research investigating the role of endothelial cells and the molecule CD93 in Idiopathic Nephrotic Syndrome in children, aiming to identify biomarkers and therapeutic targets.
Description
Idiopathic Nephrotic Syndrome (INS) is a devastating kidney disease for children, and the cause is unknown. The project proposes a novel role for endothelial cells, especially the endothelial molecule CD93, in INS. The research involves cell culture, animal models, and human studies to better understand disease mechanisms and identify potential treatments.