Award
National Institute of Neurological Disorders and Stroke 5R01NS136475-03
Identifying and Targeting 3D Regulatory Nodes that Maintain Glioblastoma Programs
Recipient
WEILL MEDICAL COLL OF CORNELL UNIV
Award Amount
$675,615.00
Ceiling
$675,615.00
Awarded
April 17, 2026
Identifier
5R01NS136475-03
Award for research on glioblastoma regulatory nodes using advanced assays and computational methods, funded by NIH with $675,615.
Description
The project focuses on uncovering and targeting central regulatory nodes in glioblastoma (GBM) using advanced chromatin topology assays, computational modeling, network analysis, epigenetic engineering, and proteomics. The research aims to characterize heterogeneity of 3D regulatory networks, predict and target candidate hubs, and uncover critical players and vulnerabilities. The project is funded by NIH grant PA-20-185, with a total award amount of $675,615, starting from May 1, 2026, to April 30, 2027. The principal investigator is Effie Apostolou, an Associate Professor at Weill Medical College of Cornell University. The project involves collaboration across multiple disciplines and advanced functional assays.