Award
NIH Reporter #5R37CA246239-07
Potentiating Checkpoint Blockade by Cross-Priming Tumor-Reactive T cells with In Situ Vaccination
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Award Amount
$351,924.00
Ceiling
$351,924.00
Awarded
January 29, 2026
Identifier
5R37CA246239-07
Research project focused on enhancing cancer immunotherapy by combining checkpoint blockade with in situ vaccination to activate tumor-reactive T cells.
Description
This project involves basic immunology studies to improve understanding of in situ vaccine in banked and unidentified samples, testing the combination of checkpoint blockade and in situ vaccination, and deep profiling of tumor-specific T cells.