Award
National Cancer Institute 5R01CA266978-05
Molecular basis for aberrant de novo DNA methylation in cancer
Recipient
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
Award Amount
$532,409.00
Ceiling
$532,409.00
Awarded
January 27, 2026
Identifier
5R01CA266978-05
Research project awarded by the National Cancer Institute to study epigenetic DNA methylation mechanisms in cancer, aiming to develop inhibitors to reverse abnormal methylation patterns.
Description
The project focuses on epigenetic mechanisms of DNA methylation regulation in cancer. The project involves multidisciplinary approaches including chromatin biochemistry, structural studies, and cancer biology. The goal is to develop inhibitors targeting DNMT3A1 interactions to reverse CGI hypermethylation in cancer.