Award
NIH Reporter #5R01NS138619-02
Linking the molecular operations of cohesin to its physiological activity in the mammalian brain
Recipient
University of California, San Francisco, Department of Neurology
Award Amount
$619,474.00
Ceiling
$619,474.00
Awarded
August 15, 2025
Identifier
5R01NS138619-02
NIH research grant awarded to study the role of cohesin in brain development and neurogenesis, focusing on genome architecture, gene expression regulation, and neurodevelopmental disorders.
Description
This research grant investigates how cohesin influences genome structure and gene regulation during brain development, with implications for understanding neurodevelopmental and intellectual disorders. The project aims to study cohesin activity and dynamics in vivo, understand the regulation of neuronal surface diversity during brain development, and link cohesin operations to neural wiring and circuit assembly.