Award
National Institute of Allergy and Infectious Diseases PA-23-272
Defining Immune Dysfunction in Chronic Hepacivirus Infection at Single Cell Resolution
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Award Amount
$1.00
Ceiling
$1.00
Awarded
July 15, 2025
Identifier
PA-23-272
Research project focused on studying immune dysfunction and T cell exhaustion in chronic hepacivirus infection using single-cell resolution techniques.
Description
This project aims to perform high-resolution immunological characterizations of a murine model of chronic hepacivirus infection to study immune dysfunction and T cell exhaustion. It involves modeling transcriptional regulatory networks and defining phenotypic features of exhausted T cell lineages. The project provides training in cutting-edge single-cell and immunological techniques.