Award
National Institute of General Medical Sciences 5R35GM146779-04
A physiological and translational liver model to study the metabolism-modulating roles of extracellular matrix microstructures
Recipient
University of Maryland Baltimore County, Baltimore, MD
Award Amount
$333,124.00
Ceiling
$333,124.00
Awarded
July 15, 2025
Identifier
5R35GM146779-04
Development of a liver model to study extracellular matrix effects on metabolism, targeting fibrosis therapy advancements.
Description
The project aims to develop a new liver modeling technology that recapitulates key liver niche properties with simple operations. The research will investigate how ECM microstructures affect hepatic metabolism, focusing on fibrosis conditions. The work is high in novelty, with potential significant impact on pharmaceutical development and fibrosis therapy.