Award
NIH Reporter #5R01AG085643-03
Influence of the Menopausal Transition and Lifetime Ovarian Exposure on Neural Metabolism, Connectivity and Pathology
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$825,324.00
Ceiling
$825,324.00
Awarded
February 24, 2026
Identifier
5R01AG085643-03
NIH research grant to study the impact of menopausal transition and ovarian hormone exposure on neural metabolism, connectivity, and Alzheimer's disease pathology in women.
Description
This NIH-funded research project aims to investigate the neural effects of menopause on Alzheimer’s disease risk, focusing on ovarian hormone exposure, brain metabolism, and connectivity. The study will follow women through the menopausal transition, utilizing advanced imaging techniques, and compare findings with pre- and postmenopausal groups to understand protective factors and mechanisms underlying AD pathology.