Award
National Institute of Mental Health 1RF1MH130391-01A1
High-throughput engineering of ligand-selective fluorescent biosensors for detecting endogenous and exogenous opioids
Recipient
University of Washington
Award Amount
$2,510,153.00
Ceiling
$2,510,153.00
Awarded
April 13, 2023
Identifier
1RF1MH130391-01A1
Award for developing advanced fluorescent biosensors to detect opioid neuropeptides in the brain, using a high-throughput platform to accelerate sensor engineering for neuroscience and therapeutic research.
Description
Development of genetically-encoded fluorescent protein sensors for precise monitoring of opioid neuropeptides in vivo using a novel high-throughput platform to accelerate sensor engineering, enabling detection of neuronal signals with high accuracy to aid neuroscience research and therapeutic development.