# NIH Reporter #1R01CA303943-01A1

Randomized Trial of a Novel Intervention to Increase Endocrine Therapy Adherence among Depressed Breast Cancer Survivors

**Recipient:** University of Colorado, Boulder, CO, USA

**Award Amount:** $653,413.00
**Ceiling:** $653,413.00

**Awarded:** September 17, 2026

**Identifier:** 1R01CA303943-01A1

A research project funded by the National Cancer Institute to test a novel intervention (REACH+) aimed at improving medication adherence among depressed breast cancer survivors through behavioral strategies and telehealth support.

### Description

This project evaluates an innovative, community-embedded intervention (REACH+) focused on breast cancer survivors at high risk of poor adherence to oral endocrine therapy. The intervention combines personal values-based strategies with behavioral treatments for depression, delivered via online sessions supported by telehealth coaching and personalized decision trees to manage side effects. The study aims to assess the short-term and long-term effects of REACH+ on medication adherence, persistence, side effects, depression, and quality of life.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11359511)