Award
National Cancer Institute 5R01CA266100-05
Deciphering the function of the APE2 nuclease during repair by alternative end-joining and its role in HR-deficient cells
Recipient
Nausica C. Arnoult
Award Amount
$351,029.00
Ceiling
$351,029.00
Awarded
January 26, 2026
Identifier
5R01CA266100-05
Research project funded by the National Cancer Institute to study the function of APE2 nuclease in DNA repair and its implications in HR-deficient cancer cells.
Description
This project involves research on the APE2 nuclease's role in DNA repair pathways, specifically in the context of homologous recombination deficiency in cancer cells. The research aims to characterize the molecular function of APE2 and explore its potential as a therapeutic target.