Award
National Institute of General Medical Sciences 5R01GM120430-08
Mapping deep evolutionary divergences in cellular models of stress response
Recipient
University of California Berkeley
Award Amount
$460,168.00
Ceiling
$460,168.00
Awarded
February 25, 2025
Identifier
5R01GM120430-08
This award supports research on evolutionary genetics using RH-seq to map trait variation across species, focusing on yeast thermotolerance and mouse cellular senescence.
Description
Understanding how nature builds new traits is a fundamental goal of evolutionary genetics. This project develops RH-seq, an approach for unbiased mapping of natural trait variation applicable to reproductively isolated species, using yeast and mouse models to study polygenic traits and cellular senescence.