Award
National Institute of General Medical Sciences 5R35GM157320-02
How cell maturation is regulated by circadian and metabolic rhythms
Recipient
University of Pennsylvania, Philadelphia, PA, United States
Award Amount
$406,250.00
Ceiling
$406,250.00
Awarded
April 29, 2026
Identifier
5R35GM157320-02
Research project funded by the National Institute of General Medical Sciences to study the influence of circadian and metabolic rhythms on cell maturation and maintenance, using gene expression mapping and gene editing techniques.
Description
The overall goal of this research is to understand how circadian and metabolic rhythms influence cell maturation and maintenance of cell function, with implications for disease diagnosis and treatment. The study will utilize in situ multimodal mapping of gene expression and in vivo gene editing in human and mouse models.