Award
National Institute of Allergy and Infectious Diseases 1R21AI185859-01A1
Development of mosaic enterovirus mRNA vaccine to prevent hand, foot and mouth disease
Recipient
CHILDREN'S MERCY HOSP (KANSAS CITY, MO)
Award Amount
$433,175.00
Ceiling
$433,175.00
Awarded
June 26, 2025
Identifier
1R21AI185859-01A1
NIH/NIAID awarded a grant to develop a mosaic enterovirus mRNA vaccine to prevent hand, foot and mouth disease, focusing on computational antigen design and therapeutic antibody development.
Description
The project aims to develop a broad mosaic multivalent HFMD mRNA vaccine and isolate broadly neutralizing antibodies. The work involves computational antigen design, mRNA-encoded VLP technology, and therapeutic antibody development.