Award
NIH Reporter #5K23DK138261-03
Contribution of Nutrient Delivery Rate to Gut-Brain Axis Signaling in Obesity and Bariatric Surgery
Recipient
LSU PENNINGTON BIOMEDICAL RESEARCH CTR, BATON ROUGE, LA, UNITED STATES
Award Amount
$178,740.00
Ceiling
$178,740.00
Awarded
April 27, 2026
Identifier
5K23DK138261-03
The award supports research on how rapid nutrient delivery after bariatric surgery affects gut-brain signaling and weight loss, using clinical and imaging methods to understand physiological changes and feeding behavior.
Description
This project investigates the mechanisms underlying sustained weight loss after bariatric surgery, focusing on the role of rapid nutrient delivery in gut-brain axis signaling. It aims to test hypotheses related to nutrient delivery, gut peptide secretion, brain responses, and nutrient absorption differences between types of bariatric surgery, using enteral nutrient infusion combined with fMRI.