Award
National Cancer Institute 1R01CA301464-01A1
Cystoscopy-augmenting tools to improve the sensitivity and specificity of detection of urothelial carcinoma in situ
Recipient
Vanderbilt University, Nashville, TN, United States
Award Amount
$2,958,465.00
Ceiling
$2,958,465.00
Awarded
September 19, 2025
Identifier
1R01CA301464-01A1
This award funds the development and clinical evaluation of advanced cystoscopy tools to enhance detection of bladder cancer, specifically urothelial carcinoma in situ, improving patient outcomes and reducing unnecessary biopsies.
Description
Development of a multimodal tool combining real-time digitally stained white light cystoscopy (dsWLC) and polarization-sensitive optical coherence tomography (PS-OCT) to improve detection of urothelial carcinoma in situ during in-office surveillance, aiming to increase sensitivity and specificity compared to current standards.