Award
National Institute of Allergy and Infectious Diseases 1R56AI203554-01
Deciphering the role of HLA-F and KIR3DS1 on NK function and HIV pathogenesis
Recipient
GEORGE WASHINGTON UNIVERSITY, WASHINGTON, DC, UNITED STATES
Award Amount
$781,999.00
Ceiling
$781,999.00
Awarded
August 07, 2026
Identifier
1R56AI203554-01
Research project investigating the role of HLA-F and KIR3DS1 interactions on NK cell function to develop HIV cure strategies.
Description
The project aims to understand mechanisms that contribute to immune-mediated control of HIV infection, focusing on the interaction between HLA-F and KIR3DS1 on Natural Killer (NK) cells. The study will evaluate genetic polymorphisms, cytokine effects, and the impact of clinical interventions on NK cell function and HIV reservoir dynamics.