Award
NIH Reporter #11310771
Mechanisms by which PIM kinase modulates the effector function of autoreactive CD8 T cells in type 1 diabetes
Recipient
Medical College of Wisconsin
Award Amount
$55,114.00
Ceiling
$55,114.00
Awarded
April 01, 2026
Identifier
11310771
Research project funded by NIDDK to study how PIM kinase affects autoreactive CD8 T cells in type 1 diabetes, potentially identifying new therapeutic targets.
Description
The project aims to elucidate molecular mechanisms regulating autoreactive CD8 T cell function in type 1 diabetes, focusing on the role of PIM1 kinase. The research will be conducted at the Medical College of Wisconsin and Versiti Blood Research Institute. The project includes bioinformatic training, presentations at national meetings, and manuscript publications. The project may identify PIM1 as a novel therapeutic target for T1D.