Award
NIH Reporter #5F32DA062455-02
Investigating the role of dorsal raphe nucleus enkephalin neurons in motivational and affective behaviors during chronic pain
Recipient
Washington University, Saint Louis, MO, United States
Award Amount
$82,348.00
Ceiling
$82,348.00
Awarded
February 09, 2026
Identifier
5F32DA062455-02
The award funds research to understand how enkephalin neurons in the dorsal raphe nucleus affect motivation and emotions during chronic pain, using advanced neurotechnologies to identify new pain therapies.
Description
This project aims to elucidate the role of endogenous opioids in the dorsal raphe nucleus in modulating pain and emotional behaviors during chronic pain states. Using cutting-edge neurotechnologies, the study will explore how enkephalinergic neurons influence pain perception and affective dysregulation, potentially leading to new therapeutic targets.