Award
National Institute of Allergy and Infectious Diseases 1R01AI196453-01
Complement convertase imaging techniques for optimization of complement therapeutic amelioration of antibody mediated rejection
Recipient
Northwestern University
Award Amount
$3,267,712.00
Ceiling
$3,267,712.00
Awarded
March 27, 2026
Identifier
1R01AI196453-01
Development of non-invasive fluorogenic probes to image complement activation in antibody-mediated rejection, using murine and porcine models to optimize therapeutic strategies.
Description
This project aims to develop non-invasive imaging techniques to assess complement activation in antibody-mediated rejection, with potential clinical translation using murine and porcine models.