Award
National Institute of Allergy and Infectious Diseases 1R15AI183099-01
Causes and consequences of virulence factor attenuation in Mycoplasma pneumoniae biofilms
Recipient
Miami University Oxford
Award Amount
$427,996.00
Ceiling
$427,996.00
Awarded
January 10, 2024
Identifier
1R15AI183099-01
NIH awarded a grant to Miami University Oxford to study the attenuation of virulence factors in Mycoplasma pneumoniae biofilms and its impact on chronic respiratory diseases, with a goal to develop therapeutic strategies.
Description
This NIH grant project aims to understand how Mycoplasma pneumoniae attenuates virulence factor production during biofilm growth and how this affects chronic respiratory diseases such as pneumonia and asthma. The research focuses on the role of oxygen levels in regulating virulence factor production and the development of therapeutic strategies to reduce morbidity associated with chronic infection.