Award
National Cancer Institute 7R37CA233691-08
Combinational Targeting the Feed-forward Epigenetic Circuitry in Mixed Lineage Leukemia
Recipient
Mayo Clinic Rochester
Award Amount
$280,084.00
Ceiling
$280,084.00
Awarded
April 27, 2026
Identifier
7R37CA233691-08
Award for research on epigenetic targeting in mixed lineage leukemia to develop combination therapies and genetic screening methods.
Description
The project focuses on epigenetic mechanisms in leukemia, specifically targeting the feed-forward circuitry involving DOT1L, PHF20, and KAT8. The research aims to develop combination therapies and novel genetic screening approaches. The award is part of NIH's efforts to find targeted treatments for leukemia.