Award
NIH Reporter #11331294
Boosting protein synthesis using antisense oligonucleotides to treat neurodegeneration
Recipient
Washington University
Award Amount
$36,570.00
Ceiling
$36,570.00
Awarded
May 19, 2026
Identifier
11331294
Award to Washington University for research on using antisense oligonucleotides to boost protein synthesis for treating neurodegeneration, led by Ben David Boros, funded by the National Institute on Aging with $36,570 for fiscal year 2026.
Description
The project aims to evaluate antisense oligonucleotides targeting 3'UTRs to upregulate proteins involved in neuroprotection and treat age-related neurodegenerative diseases. The project involves pre-clinical models and aims to support clinical testing. It focuses on mRNA regulation, antisense oligonucleotides, neurodegenerative diseases, and gene therapy.