Award
NIH Reporter #1ZIAHG200400-08
Natural history and evaluation of abnormal or nonreportable NIPT results and its association with maternal neoplasia
Recipient
NATIONAL HUMAN GENOME RESEARCH INSTITUTE
Award Amount
$74,953.00
Ceiling
$74,953.00
Awarded
January 01, 2025
Identifier
1ZIAHG200400-08
This award funds research on the natural history and evaluation of abnormal or nonreportable noninvasive prenatal testing (NIPT) results, investigating their link to maternal neoplasia through cfDNA analysis and multidisciplinary follow-up.
Description
The project studies noninvasive screening for fetal aneuploidy by sequencing cell-free DNA fragments in maternal blood, focusing on abnormal or nonreportable NIPT results and their association with maternal neoplasia. It involves multidisciplinary analysis and follow-up of pregnant women with abnormal cfDNA results to evaluate maternal neoplasia, emphasizing the importance of cfDNA sequencing patterns in cancer risk assessment during pregnancy.