Award
National Heart, Lung, and Blood Institute 5R01HL136590-09
Computational Pipeline for Identification of Disease-Causing Variants in Genes of the Cardiac Sarcomere
Recipient
Yale University
Awarded
August 04, 2026
Identifier
5R01HL136590-09
Award for developing computational methods to identify disease-causing genetic variants in cardiac sarcomere genes to improve diagnosis and risk assessment of heart diseases.
Description
NIH grant opportunity for research on biophysically detailed multiscale models related to cardiac gene mutations and their impact on cardiomyopathies. The project aims to develop computational pipelines for classifying sarcomeric variants of unknown significance to aid in early diagnosis and risk stratification of heart diseases.