Award
National Cancer Institute 1R01CA300773-01A1
Investigating the chromatin remodeling complex PBAF in small cell lung cancer
Recipient
Yale University
Award Amount
$577,750.00
Ceiling
$577,750.00
Awarded
June 03, 2026
Identifier
1R01CA300773-01A1
NIH awarded a grant to investigate the role of the PBAF chromatin remodeling complex in small cell lung cancer, focusing on its function, mechanisms, and potential therapeutic strategies using advanced models and profiling techniques.
Description
This NIH grant supports research on the role of the PBAF chromatin remodeling complex in small cell lung cancer, including aims to establish the importance of PBAF during cancer initiation, elucidate underlying mechanisms, and evaluate therapeutic strategies. The project leverages innovative animal models and state-of-the-art epigenomic profiling techniques to advance understanding and treatment of this aggressive cancer.