Award
NIH Reporter #1K99DC023302-01
Recovery from Post-Stroke Aphasia With rTMS Targeting The Anterior Temporal Lobe: Interhemispheric Activation Changes And Lesion-Connectome-Based Predictive Outcomes
Recipient
University of South Carolina at Columbia, Department of Psychology
Award Amount
$146,004.00
Ceiling
$146,004.00
Awarded
March 19, 2026
Identifier
1K99DC023302-01
A NIH-funded project to improve recovery from post-stroke aphasia using targeted rTMS and neuroimaging to understand brain activation changes and predict outcomes based on lesion and connectome data.
Description
This project aims to tailor repetitive Transcranial Magnetic Stimulation (rTMS) targets to the clinical profile of post-stroke aphasia, focusing on lexicosemantic impairments to enhance recovery. Functional Magnetic Resonance Imaging (fMRI) will provide insights into the effects of facilitatory versus inhibitory stimulation on interhemispheric balance. The study will generate data on how lesion localization and brain connectivity influence individual responses to rTMS, explaining variability in treatment efficacy.