Award
National Heart, Lung, and Blood Institute 4R00HL166778-03
Lipid peroxidation- and pyroptosis-induced tissue factor activation in pathogen-induced blood coagulation
Recipient
National Heart Lung and Blood Institute (NHLBI)
Award Amount
$249,000.00
Ceiling
$249,000.00
Awarded
June 03, 2026
Identifier
4R00HL166778-03
Research project funded by the National Heart Lung and Blood Institute to study tissue factor activation mechanisms in pathogen-induced blood coagulation, aiming to find therapeutic targets to reduce pathological coagulation.
Description
The project focuses on investigating mechanisms of TF activation related to lipid peroxidation and programmed cell death in bacterial and viral infections. The study aims to identify therapeutically targetable enzymes to mitigate pathological coagulation. The award is funded by the NIH and is part of a multi-year research effort.