Award
National Institute on Aging 5R00AG064143-05
The role of unacylated ghrelin on age-associated progressive muscle weakness and cachexia elicited by cancer
Recipient
Wake Forest University Health Sciences
Awarded
January 29, 2024
Identifier
5R00AG064143-05
Research project awarded by the National Institute on Aging to study the effects of unacylated ghrelin on muscle weakness and cachexia in aging and cancer, led by a postdoctoral fellow at Wake Forest University.
Description
The project focuses on testing the impact of unacylated ghrelin on skeletal muscle weakness in aging and cancer cachexia, with aims to determine its preventive effects on neurogenic atrophy, contractile dysfunction, and rapid wasting. The principal investigator is a postdoctoral fellow at Wake Forest University Health Sciences, mentored by Dr. Holly Van Remmen. The project involves advanced molecular biology and physiology techniques, with potential for clinical trials due to the safety profile of UnAG.