Award
National Institute of General Medical Sciences 5R01GM101255-12
Heterochromatin and Toxic Y Chromosomes
Recipient
University of California Berkeley, Department of Biology
Award Amount
$384,584.00
Ceiling
$384,584.00
Awarded
January 29, 2026
Identifier
5R01GM101255-12
NIH grant awarded to University of California Berkeley for research on epigenetic conflicts on Y chromosomes and heterochromatin, with a focus on aging and disease implications.
Description
This NIH project focuses on the epigenetic regulation of heterochromatin and its impact on Y chromosome toxicity, aging, and disease. The research uses Drosophila as a model to investigate epigenetic conflicts on Y chromosomes, focusing on how repressive chromatin states interact with actively transcribed genes, aiming to develop therapeutic strategies to reset dysregulated epigenetic states.