Award
National Institute of Allergy and Infectious Diseases 5R01AI153605-05
Commensal control of C. difficile virulence
Recipient
Brigham and Women's Hospital, Boston, MA, USA
Award Amount
$603,478.00
Ceiling
$603,478.00
Awarded
January 09, 2025
Identifier
5R01AI153605-05
Research project funded by NIAID to study microbes that protect against C. difficile infections and their mechanisms, aiming to develop better therapies.
Description
Clostridioides difficile causes severe infections of the colon, infections that commonly arise after use of antibiotics that destroy healthy populations of microbes which prevent infection. Our proposed studies are defining the specific microbes that provide this protection, and their mechanisms of action. This knowledge will be used to help create more defined, effective and safe therapies for this disease.