Award

National Institute of Allergy and Infectious Diseases 1K99AI197987-01

Pathways and Mechanisms of Drug Resistance Evolution in HIV

Recipient

SALK INSTITUTE FOR BIOLOGICAL STUDIES

Award Amount

$161,868.00

Ceiling

$161,868.00

Awarded

June 08, 2026

Identifier

1K99AI197987-01

Research project funded by NIAID to study HIV drug resistance evolution using computational and structural biology methods combined with AI to inform new therapies.

Description

This project aims to elucidate the mutational pathways and molecular mechanisms through which resistance to antiretroviral therapy (ART) develops in HIV. The research will utilize a combination of computational modeling, structural biology, and artificial intelligence to predict and understand resistance evolution, ultimately informing the development of next-generation therapeutics and surveillance tools.

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