Award
National Institute of Allergy and Infectious Diseases 1R21AI193492-01
Engineered Microbes to Mitigate Intestinal Radiation Damage
Recipient
Baylor College of Medicine, Houston, TX
Award Amount
$160,125.00
Ceiling
$160,125.00
Awarded
July 30, 2025
Identifier
1R21AI193492-01
This NIH-funded project explores using engineered microbes to protect intestinal stem cells from radiation damage, aiming to develop treatments for acute radiation syndrome in the gastrointestinal tract.
Description
The project aims to evaluate the capacity of engineered intestinal microbial organisms to deliver factors that enhance and promote the activity of radioresistant intestinal stem cells to mitigate gastrointestinal acute radiation syndrome (GI-ARS) using mouse models. This research is part of NIH's efforts to develop medical countermeasures for nuclear incidents.