Award

National Institute of Mental Health 5R01MH129492-05

Neural Mechanisms of Rule-Based Behavior

Recipient

Princeton University, Department of Neurosciences

Award Amount

$403,058.00

Ceiling

$403,058.00

Awarded

February 12, 2026

Identifier

5R01MH129492-05

Research grant to study the neural basis of rule-based behavior to understand cognitive deficits in mental illnesses such as schizophrenia, aiming to develop new diagnostics and treatments.

Description

This project will investigate how the brain uses rules to guide our behavior. Rules define how we should act in a given situation and so disrupting one’s ability to learn and follow rules carries significant social and economic costs for many neuropsychiatric and neurodegenerative diseases, including schizophrenia. Our work will provide insight into the neural mechanisms of rule-based behavior, providing the foundation for a better understanding of these diseases.

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