Award
NIH Reporter #5R01MH128286-05
Individualized brain biomarkers of late life depression: contributions to heterogeneity and resilience
Recipient
Washington University
Award Amount
$464,438.00
Ceiling
$464,438.00
Awarded
May 20, 2026
Identifier
5R01MH128286-05
Research project funded by NIMH to identify brain biomarkers and factors influencing heterogeneity and resilience in late-life depression, aiming to improve treatment and prevention.
Description
This project aims to distinguish brain profiles linked to differences in depression symptoms, severity, age of first depression, and number of episodes. It will also identify environmental and psychological stress factors influencing vulnerability or resilience to depression. The research focuses on brain biomarkers, clinical heterogeneity in late-life depression, longitudinal brain changes, and resilience and vulnerability factors to improve treatment and prevention strategies for late-life depression.