Award
National Institute of Allergy and Infectious Diseases 5U01AI169385-05
Defining the mechanisms of HIV resistance to bNAbs in humans
Recipient
Rockefeller University, New York, NY
Award Amount
$1,569,774.00
Ceiling
$1,569,774.00
Awarded
May 01, 2026
Identifier
5U01AI169385-05
This award funds research to understand how HIV resists broadly neutralizing antibodies, aiming to develop improved antibody therapies to prevent resistance.
Description
The project focuses on understanding HIV resistance mechanisms to broadly neutralizing antibodies (bNAbs). It involves deep sequencing, mapping resistance mutations, studying resistant variants, and developing computational models. The goal is to design better bNAb therapies to prevent resistance.